| ncRNA name | TAK1 siRNA |
| ncRNA Category | siRNA |
| Disease name | proliferative vitreoretinopathy (PVR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human RPE cell line ARPE-19 |
| Methods | ELISA, RT-PCR, siRNA transfection, immunoprecipitation, immunoblot, immunofluorescence |
| Expression pattern | associated |
| Functional description | The TNF-α–induced phosphorylation of p38MAPK was inhibited by siTAK1 in ARPE-19 cells. Additionally, the high level of expression of mesenchymal markers such as fibronectin and α-SMA that was caused by TNF-α treatment was reduced by siTAK1 transfection |
| PubMed ID | 25783601 |
| Year | 2015 |
| Title | Merlin Regulates Epithelial-to-Mesenchymal Transition of ARPE-19 Cells via TAK1-p38MAPK-Mediated Activation. |
| Drug-related ncRNA | NO |
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